Webinar - October 31, 2013

The Story of a Pill–Starring Water Activity


Dr. Brady Carter, METER’s Director of Food Science, discusses how to use water activity in pharmaceutical products to control pill stability and extend shelf life.

Topics covered include:

  • How to assess the stability of a pill
  • Basics of water activity
  • Moisture content vs. water activity
  • How to measure water activity
  • Moisture sorption isotherms and how to use them
  • Preventing microbial growth
  • Preventing API degradation
  • Gel coating integrity
  • Moisture migration in capsules
  • Determining relative hygroscopicity
  • Water activity and glass transition
  • Determining deliquescence point
  • Excipients
  • Storage humidity
  • Packaging for extended shelf life
  • An accelerated stability testing procedure